WUJing-jing,GUIPing,GUOFeng-qiao.SPE-UPLC-MS/MS for Determination of 17 PFCs in Water[J].China Water & Wastewater,2022,38(12):28-36.
SPE-UPLC-MS/MS for Determination of 17 PFCs in Water
China Water & Wastewater[ISSN:1000-4062/CN:12-1073/TU]
volume:
第38卷
Number:
第12期
Page:
28-36
Column:
Date of publication:
2022-06-17
- Keywords:
- solid phase extraction; UPLC-MS/MS; background interference; PFCs
- Abstract:
- A method for determination of 17 perfluorinated compounds (PFCs) in drinking water and source water was established based on solid phase extraction-ultra?performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The water sample was extracted by WAX solid phase extraction (SPE) column and determined by UPLC-MS/MS. The separation was performed on a Cortecs C18 column with mobile phases of water containing 2 mmol/L ammonium acetate and methanol/acetonitrile (80∶20), and PFCs were analyzed by using multiple reaction monitoring (MRM) mode, negative electrospray ionization and negative ion scanning. Background interference was eliminated in the whole process of sampling, sample pre-treatment and detection through optimization of the pipe material and trap column. The linear correlation coefficients (R2) of 17 PFC standard curves were all greater than 0.99, and the limits of quantification ranged from 0.083 ng/L to 1.56 ng/L. When adding standard solutions of 4 different concentrations, the recoveries of drinking water (product water and pipe water) were 65.0%-117.8% and the relative standard deviations (RSD) were 0.13%-17.93%. The recoveries of source water were 67.0%-117.8%, and the RSD were 0.60%-18.71%. Compared with 11 PFCs detection methods proposed in the national standard, this method has the advantages of high sensitivity, good stability and high detection efficiency, which can detect 17 trace PFCs in drinking water from source to tap.
Last Update:
2022-06-17