LANG Lang,DONG Xiao qi,DI Jing bo.Determination of 11 Antibiotics in Harbin Section of Songhua River by SPE-HPLC[J].China Water & Wastewater,2018,34(20):114-118.
SPE-HPLC法测定松花江哈尔滨段水样中11种抗生素
- Title:
- Determination of 11 Antibiotics in Harbin Section of Songhua River by SPE-HPLC
- 文章编号:
- 1000-4602(2018)20-0114-05
- Keywords:
- Songhua River basin; antibiotics; solid phase extraction; high performance liquid chromatography
- 分类号:
- TU991
- 文献标志码:
- C
- 摘要:
- 应用SPE-HPLC法检测松花江哈尔滨段4种喹诺酮类、3种磺胺类和4种大环内酯类抗生素的含量。实验结果表明，固相萃取小柱的富集效果好，抗生素在10~2 000 μg/L浓度范围内线性关系良好，精密度、重现性、回收率良好，符合试验要求。测定结果表明，松花江哈尔滨段选取的四个监测断面均存在抗生素的污染，朱顺屯断面主要是喹诺酮类抗生素的污染，阿什河口下和呼兰河口下断面主要是磺胺类和大环内酯类抗生素的污染，大顶子山断面仅在6月份检出红霉素。经分析可知抗生素污染主要来自沿岸企业废水和生活污水，同时受径流量、流速因素以及气候的影响。
- Abstract:
- The content of four quinolones, three sulfonamides and four macrolide antibiotics in the Harbin section of Songhua River was detected by SPE-HPLC. The experimental results showed that the solid phase extraction cartridge had a good enrichment effect. A good linear relationship had been gained in the antibiotics concentration range of 10-2 000 μg/L, and the precision, reproducibility and recovery rate all reached the test requirements. The test results showed that there were antibiotic pollution in the four monitoring sections selected in the Harbin section of Songhua River. Quinolone antibiotics were the main pollutants in Zhushuntun section. Sulfonamides and macrolides were the main pollutants in Ashihekouxia and Hulanhekouxia sections. Erythromycin were detected in Dadingzishan section only in June. According to the analysis results, the pollution of antibiotics mainly came from coastal enterprise wastewater and domestic sewage, and was also affected by other factors such as runoff, flow rate factors and climate.
参考文献/References:
［1］Bruce J R,Paul K S L,Michael M. Emerging chemicals of concern: Pharmaceuticals and personal care products(PPCPs) in Asia,with particular reference to Southern China［J］. Mar Pollut Bull,2005,50(9):913-920.
［2］Roman H,Thomas T,Klaus H,et al. Occurrence of antibiotics in the aquatic environment［J］. Sci Total Environ,1999,225(1/2):109-118.
［3］Yan C,Yang Y,Zhou J,et al. Antibiotics in the surface water of the Yangtze Estuary:Occurrence,distribution and risk assessment［J］. Environ Pollut,2013,175:22-29.
［4］Chen J Q,Guo R X. Access the toxic effect of the antibiotic cefradine and its UV light degradation products on two freshwater algae［J］. J Hazard Mater,2012,209/210:520-523.
［5］樊庆锌,杨先兴,邱微. 松花江哈尔滨段城市水环境质量评价［J］. 中国环境科学,2014,34(9)：2292-2298.Fan Qingxin,Yang Xianxing,Qiu Wei. Study on water environmental quality in Harbin section of the Songhua River［J］. China Environmental Science,2014,34(9):2292-2298（in Chinese）.
［6］Li W,Shi Y,Gao L,et al. Occurrence and removal of antibiotics in a municipal wastewater reclamation plant in Beijing,China［J］. Chemosphere,2013,92(4):435-444.
［7］杨先兴. 松花江哈尔滨段水环境质量时空变化特征分析［D］.哈尔滨:哈尔滨工业大学,2014.Yang Xianxing. Research on Temporal and Spatial Variation of Water Environmental Quality in Harbin Section of the Songhua River［D］. Harbin:Harbin Institute of Technology,2014（in Chinese）.
［8］McArdell C,Molnar E,Suter M JF,et al. Occurrence and fate of macrolide antibiotics in wastewater treatment plants and in the Glatt Valley Watershed,Switzerland［J］. Environ Sci Technol,2003,37(24):5479-5486.
［9］刘丹丹,韩帅. 松花江哈尔滨段枯水期水环境质量评价［J］. 黑龙江环境通报,2015,39(2):27-32.Liu Dandan,Han Shuai. Evaluate the water environmental quality of the Songhua River in the dry season Harbin section［J］. Heilongjiang Environmental Journal,2015,39(2):27-32（in Chinese）.
［10］李亚男. 大顶子山工程建成后松花江哈尔滨段水质分析与污染控制［D］.哈尔滨:哈尔滨工业大学,2012.Li Yanan. Study on Water Quality Analysis and Pollution Control in Songhua River Harbin Section after Dadingzishan Project Completed［D］. Harbin:Harbin Institute of Technology,2012(in Chinese）.
［11］邵雪. 松花江哈尔滨段水质变化趋势分析与控制对策研究［D］.哈尔滨:哈尔滨工业大学,2011.Shao Xue. Analysis the Songhua River in Harbin Section’s Water Quality Trend and Research on the Control Measures［D］. Harbin:Harbin Institute of Technology,2011（in Chinese）.
［12］李俊锁,邱月明,王超. 兽药残留分析［M］. 上海:上海科学技术出版社,2002.Li Junsuo,Qiu Yueming,Wang Chao. Veterinary Drug Residue Analysis［M］. Shanghai:Shanghai Scientific & Technical Publishers,2002（in Chinese）.
备注/Memo
基金项目：哈尔滨市青年项目(2013RFQXJ054)2018年哈尔滨商业大学研究生创新科研项目（YJSCX2018-549HSD）；黑龙江省教育厅科学技术研究项目（12541188）
作者简介：郎朗（1979-），女，满族，黑龙江大庆人，博士，副研究员，研究方向为环境生态学、环境毒理学。
E-mail:lang8968@163.com
收稿日期：2018-07-06
讣告：
本刊编委、清华大学环境学院刘文君教授，因病医治无效，于2018年9月29日1时在北