[1]吴斌,郝怡菲,苏宇亮,等.在线固相萃取-UHPLC-MS/MS测定水中全氟化合物[J].中国给水排水,2026,42(2):132-136.
　WUBin,HAOYifei,SUYuliang,et al.Determination of Perfluorinated Compounds in Drinking Water Using Online Solid-phase Extraction Coupled with UHPLC-MS/MS[J].China Water & Wastewater,2026,42(2):132-136.
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在线固相萃取-UHPLC-MS/MS测定水中全氟化合物

中国给水排水[ISSN:1000-4062/CN:12-1073/TU] 卷: 第42卷 期数: 2026年第2期 页码: 132-136 栏目: 出版日期: 2026-01-17
Title:
Determination of Perfluorinated Compounds in Drinking Water Using Online Solid-phase Extraction Coupled with UHPLC-MS/MS
作者:
吴斌， 郝怡菲， 苏宇亮， 沈会栋， 练紫琦， 曹家瑶， 韩国杭， 方黎
（珠海水务环境控股集团有限公司，广东 珠海 519020）
Author(s):
WU　Bin， HAO　Yifei， SU　Yuliang， SHEN　Huidong， LIAN　Ziqi， CAO　Jiayao， HAN　Guohang， FANG　Li
（Zhuhai Water Environment Holdings Group Ltd.， Zhuhai 519020， China）
关键词:
在线固相萃取;  超高效液相色谱-串联质谱法;  全氟化合物;  生活饮用水
Keywords:
online solid-phase extraction;  UHPLC-MS/MS;  perfluorinated compounds (PFCs);  drinking water
摘要:
采用在线固相萃取-超高效液相色谱-串联质谱联用的技术，建立了生活饮用水及水源水中15种全氟化合物同时分析的方法。5 mL样品经HLB固相萃取小柱在线富集、净化并洗脱后，通过超高效液相色谱-串联质谱进行定量检测。15种全氟化合物在1~200 ng/L范围内具有良好的线性关系，相关系数均大于0.99，方法检测限为1.04~3.37 ng/L，加标回收率在84.7%~114.0%之间。该方法具有操作简便、灵敏度高、回收率高、重现性好、分析时间短、节约溶剂等特点，对广东地区某城市的出厂水、地表水的检测表明，可实际应用于生活饮用水及水源水中全氟化合物的检测分析。
Abstract:
A method for the simultaneous analysis of 15 perfluorinated compounds (PFCs) in drinking water and source water was developed using online solid-phase extraction coupled with ultra-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS). A 5 mL sample was enriched, purified, and eluted online using an HLB solid-phase extraction column, followed by quantitative analysis via UHPLC-MS/MS. The 15 perfluorinated compounds exhibited excellent linear relationships within the concentration range of 1-200 ng/L. All correlation coefficients exceeded 0.99. The detection limits of the methods ranged from 1.04 ng/L to 3.37 ng/L, and the spike recoveries were between 84.7% and 114.0%. This method is characterized by simple operation, high sensitivity, high recovery, excellent reproducibility, a short analysis time, and solvent conservation. The detection of drinking water and surface water in a city in Guangdong Province demonstrated that this method could be effectively applied to the detection and analysis of PFCs in both domestic drinking water and source water.
更新日期/Last Update: 2026-01-17